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Nizoral, ketoconazole information
Other names: Perkhotal, Fungarest
Description and Notes for Nizoral cream:
Nizoral cream is used for the treatment of the following fungal infections:
Athletes Foot
Tinea
Ringworm and thrush infections of the skin and in the treatment of seborrheic dermatitus which is caused by a yeast Malassezia Ovalis.
The active ingredient in Nizoral Cream (Perkhotal, Fungarest, Ketoconazole) also interferes with androgen synthesis so it may be effective to some extent in treating androgenetic related conditions like Androgenetic Alopecia.
Dosage and Administration:
Use once daily for 2-4 weeks for most skin conditions until a few days after the disappearance of all symptoms.
The diagnosis and treatment should be reconsidered if no clinical improvement is noted after 4 weeks of therapy. General measures in regard to hygiene should be observed in order to control sources of infection and reinfection.
Directions:
Follow the directions for using this Nizoral (Perkhotal, Fungarest, Ketoconazole) provided by your doctor or pharmacist. This medicine may be taken on an empty stomach or with food. Store this medicine at room temperature. Keep your tablets in the blister pack until you take them. If you take the tablets out of the blister pack they will not keep well.
If you miss a dose and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Description and Notes for Nizoral (Perkhotal, Fungarest, Ketoconazole):
Nizoral, a broad-spectrum antifungal drug available in tablet form, may be given to treat several fungal infections within the body, including oral thrush and candidiasis.
It may also be given to treat severe, hard to treat fungal skin infections that have not cleared up after treatment with creams or ointments or the oral drug griseofulvin (Fulvicin, Grisactin).
In some people, Nizoral may cause serious or even fatal damage to the liver. Before starting to take Nizoral and at frequent intervals while you are taking it, you should have blood tests to evaluate your liver function. Tell your doctor immediately if you experience any signs or symptoms that could indicate liver damage: these include unusual fatigue, loss of appetite, nausea, vomiting, jaundice, dark urine or pale stools.
Take Nizoral exactly as prescribed.
You should keep taking the drug until tests show that your fungal infection has subsided. If you stop too soon, the infection might return.
You may want to take Nizoral tablets with meals to avoid stomach upset.
Avoid alcohol and do not take with antacids. If antacids are necessary, you should wait 2 to 3 hours before taking them.
If you miss a dose
Take the forgotten dose as soon as you remember. This will help to keep the proper amount of medicine in the body. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take double doses.
Do not take Nizoral (Perkhotal, Fungarest, Ketoconazole) if you are sensitive to it or have ever had an allergic reaction to it. Never take Nizoral together with Seldane, Hismanal, Halcion or Propulsid. Rare, but sometimes fatal reactions have been reported when these drugs are combined.
Recommended dosage for Adults
The recommended starting dose of Nizoral is a single daily dose of 200 milligrams (1 tablet).
In very serious infections, or if the problem does not clear up within the expected time, the dose of Nizoral may be increased to 400 milligrams (2 tablets) once daily. Treatment lasts at least 1 to 2 weeks, and for some infections much longer.
Fungarest - vaginal 400mg
Composition:
Each ovule contains 400 mg of the active ingredient, ketoconazole
Pharmacological Action:
Fungarest, a synthetic imidazole dioxolane derivative, has antimycotic activity against dermatophytes, yeasts and other pathogenic fungi.
Indications:
Fungarest (Perkhotal, Nizoral, Ketoconazole) are indicated for the local treatment of acute and chronic vaginal candidiasis.
Contraindications:
Fungarest is contraindicated in patients who have shown hypersensitivity to ketoconazole (or other imidazole preparations), or to any of their ingredients.
Dosage And Directions:
Acute vulvovaginal candidiasis: (i.e. fewer than 3 episodes during the previous year).
Insert one ovule 400 mg into the vagina daily for 3 to 5 consecutive days, depending on the severity of the clinical symptoms.
Chronic recurrent vulvovaginal candidiasis: (i.e. 3 or more episodes during the previous year).
Insert one ovule 400 mg into the vagina daily for 5 consecutive days, immediately after the cessation of menstruation, to be repeated if needed after successive menstrual cycles.
Side Effects:
Patients may experience a burning sensation, irritation or pruritus of the vagina and vulva.
Precautions:
If local irritation or an allergic reaction occurs, treatment should be stopped. General hygienic measures should be observed to control sources of infection and reinfection. Appropriate therapy is indicated when the sexual partner has also been infected. Nizovules do not stain skin or clothes.
Interactions:
Contact should be avoided between latex products such as contraceptive diaphragms or condoms and certain vaginal products since the rubber might be damaged, this may also apply to Nizovules.
Pregnancy and lactation:
Safety in pregnancy has not been established.
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