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Buy Uniket, isosorbide-5-mononitrate |
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Brand names: Uniket, isosorbide-5-mononitrate
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Uniket 40mg |
160 tablets, $ 112.00 USD |
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Uniket, Isosorbide-5-mononitrate is for the prophylaxis and treatment of angina pectoris
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PROPERTIES
Isosorbide-5-mononitrate is the main active metabolite of isosorbide dinitrate. The extent of bioavailability of isosorbide-5-mononitrate is 100% after oral administration and it is metabolised very slowly, therefore it has a very prolonged action (more than 12 hours). Like other nitrates, isosorbide-5-mononitrate reduces the demand of the myocardium for oxygen, thus improving myocardial oxygen balance. The action of isosorbide-5-mononitrate is the relaxation of vascular smooth muscle producing vasodilation of both veins (intense) and peripheral arteries (moderate). This vasodilation simultaneously reduces cardiac preload and afterload thereby reducing the workload of the heart, resulting in a decreased myocardial oxygen requirement and an improved oxygen demand / supply balance in the myocardium, this change is the basis of the manifestations of ischemic heart disease.
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CONTACT INFORMATION
Uniket